Article

Trans-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

2020-09-23

Abstract excerpt

<h4>ABSTRACT</h4> We assembled an ancestrally diverse collection of genome-wide association studies of type 2 diabetes (T2D) in 180,834 cases and 1,159,055 controls (48.9% non-European descent). We identified 277 loci at genome-wide significance ( p <5×10 -8 ), including 237 attaining a more stringent trans-ancestry threshold ( p <5×10 -9 ), which were delineated to 338 distinct association signals. Trans-ancestry...

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Literature Corpus work: aa0518ee-4182-5d42-87db-f36f524d2762
DOI: 10.1101/2020.09.22.20198937

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