Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Genetics of Type 2 Diabetes: Implications from Large-Scale Studies.

Current diabetes reports - 1 May 2022

DeForest Natalie, Majithia Amit R

Abstract excerpt

PURPOSE OF REVIEW: Type 2 diabetes (T2D) is a multifactorial, heritable syndrome characterized by dysregulated glucose homeostasis that results from impaired insulin secretion and insulin resistance. Genetic association studies have successfully identified hundreds of T2D risk loci implicating many genes in disease pathogenesis. In this review, we provide an overview of the recent T2D genetic studies from the...

Topics

Diabetes Mellitus, Type 2
Genetic Predisposition to Disease
Genome-Wide Association Study
Humans
Insulin Resistance
Polymorphism, Single Nucleotide
Risk Factors

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 35305202
DOI: 10.1007/s11892-022-01462-3
PMCID: PMC9072491

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetics of Type 2 Diabetes: Implications from Large-Scale Studies.PMID 35305202Read ↗

Recent advances in understanding the genetic architecture of type 2 diabetes.Semantic proximity Read ↗

The genetic architecture of type 2 diabetes.Semantic proximity Read ↗

Improving type 2 diabetes polygenic risk scores by incorporating rare, low-frequency, and population-specific variantsSemantic proximity Read ↗

Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation.Semantic proximity Read ↗

Genetic architecture of type 2 diabetes.Semantic proximity Read ↗

Genetics of Type 2 Diabetes—Pitfalls and PossibilitiesSemantic proximity Read ↗

Genetics of type 2 diabetes.Semantic proximity Read ↗

The genetics of type 2 diabetes and its clinical relevance.Semantic proximity Read ↗

Genetics of T2DM and Its Chronic Complications: Are We Any Closer to the Individual Prediction of Genetic Risk?Semantic proximity Read ↗

Genetic drivers of heterogeneity in type 2 diabetes pathophysiology.Semantic proximity Read ↗

Perspectives on genetic studies of type 2 diabetes from the genome-wide association studies era to precision medicine.Semantic proximity Read ↗

Genomics of type 2 diabetes mellitus: implications for the clinician.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.