Article
Induction of T-cell memory by a dendritic cell vaccine: a computational model
6 Mar 2014
Abstract excerpt
MOTIVATION: Although results from phase III clinical trials substantially support the use of prophylactic and therapeutic vaccines against cancer, what has yet to be defined is how many and how frequent boosts are needed to sustain a long-lasting and protecting memory T-cell response against tumor antigens. Common experience is that such preclinical tests require the sacrifice of a relatively large number of...
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