Article

The role of 5-hydroxymethylcytosine as a potential epigenetic biomarker in a large series of thyroid neoplasm

2023-06-14

Abstract excerpt

Cytosine modifications at the 5-carbon position play an important role in the regulation of gene expression, and its deregulation is considered a hallmark of cancer. Recent studies demonstrate that 5-hydroxymethylcytosine (5-hmC) generated through 5-methylcytosine (5-mC) oxidation is significantly depleted in several human cancers. Although its role in tumour progression is still unclear, 5-hmC loss has been propo...

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Literature Corpus work: a9c98e90-7ac6-59f9-8f80-ad3735fd619b
DOI: 10.21203/rs.3.rs-3034402/v1

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