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Identification of a Druggable Site on GRP78 at the GRP78-SARS-CoV-2 Interface and Compounds to Disrupt that Interface

2023-09-13

Abstract excerpt

SARS-CoV-2, the virus that causes COVID-19, led to a global health emergency that claimed the lives of millions. Despite the widespread availability of vaccines, the virus continues to exist in the population in an endemic state which allows for the continued emergence of new variants. Most of the current vaccines target the spike glycoprotein interface of SARS-CoV-2, creating a selection pressure favoring viral i...

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Literature Corpus work
a9c61e0a-37eb-5e82-89d3-6c40a6251daa
DOI
10.1101/2023.09.12.557363
Open publication

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Identification of a Druggable Site on GRP78 at the GRP78-SARS-CoV-2 Interface and Compounds to Disrupt that InterfaceDOI 10.1101/2023.09.12.557363
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