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Article

Recognition through GRP78 is enhanced in the UK, South African, and Brazilian variants of SARS-CoV-2; An in silico perspective.

Biochemical and biophysical research communications - 12 Jul 2021

Ibrahim Ibrahim M, Elfiky Abdo A, Elgohary Alaa M

Abstract excerpt

New SARS-CoV-2 variants emerged in the United Kingdom and South Africa in December 2020 in concomitant with the Brazillian variant in February 2021 (B.1.1.248 lineage) and currently sparking worldwide during the last few months. The new strain 501.V2 in South Africa bears three mutations in the spike receptor-binding domain (RBD); K417 N, E484K, and N501Y, while the Brazilian B.1.1.248 lineage has 12 mutations....

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Share to Angiotensin-Converting Enzyme 2
Share to Endoplasmic Reticulum Chaperone BiP

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heat-Shock Proteins

Share to Molecular Docking Simulation

Share to Receptors, Virus

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Share to Spike Glycoprotein, Coronavirus

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Source

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Identifiers

PMID: 34049205
DOI: 10.1016/j.bbrc.2021.05.058
PMCID: PMC8139235

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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