Article
Effects of S-Adenosylhomocysteine-Hydrolase Down-Regulation on Wnt Signaling Pathway in SW480 Cells
2023-09-15
Abstract excerpt
Disorder of S-adenosylhomocysteine hydrolase (AHCY) activity leads to the potentially lethal rare disease AHCY deficiency, first described in 2004 by Baric and co-workers [1]. In order to shed new light on molecular aspects of the disease, in particular changes at transcriptome level, we enabled knock-down of AHCY expression in model systems such as the colon cancer cell line SW480 to simulate the environment occu...
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Identifiers and source
- Literature Corpus work
- a98e8ebe-26fa-5fe4-8303-a82d7bfaed8b
- DOI
- 10.20944/preprints202309.1046.v1
