Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Wnt/β-catenin signaling induces the transcription of cystathionine-γ-lyase, a stimulator of tumor in colon cancer.

Cellular signalling - 1 Dec 2014

Fan Kun, Li Na, Qi Jingjing, Yin Peng, Zhao Chao, Wang Liying, Li Zengxia, Zha Xiliang

Abstract excerpt

Cystathionine-γ-lyase (CSE) is a major endogenous enzyme producing H2S which, as a third gasotransmitter, plays important roles in many physiological and pathological processes. The mechanism of regulating CSE gene expression is unclear and the roles of CSE/H2S in tumor also have not got a profound understanding, especially in colon cancer. Our study demonstrated that CSE gene expression was regulated by the Wnt...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alkynes
Share to Colonic Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Knockdown Techniques

Share to Glycine

Share to Mice, Nude

Share to TCF Transcription Factors

Share to Wnt Signaling Pathway

Share to Xenograft Model Antitumor Assays

Source

Identifiers

PMID: 25193114
DOI: 10.1016/j.cellsig.2014.08.023

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

Wnt/β-catenin signaling induces the transcription of cystathionine-γ-lyase, a stimulator of tumor in colon cancer.PMID 25193114Read ↗

Regulation of cystathionine gamma-lyase/H₂S system and its pathological implication.Semantic proximity Read ↗

Bioinformatics analysis and experimental validation of Cystathionine-gamma-lyase as a potential biomarker for prognosis in hepatocellular carcinomaSemantic proximity Read ↗

Cystathionine- γ-lyase promotes process of breast cancer in association with STAT3 signaling pathwaySemantic proximity Read ↗

Effects of S-Adenosylhomocysteine-Hydrolase Down-Regulation on Wnt Signaling Pathway in SW480 CellsSemantic proximity Read ↗

Sulfation of chondroitin and bile acids converges to antagonize Wnt/β-catenin signaling and inhibit APC deficiency-induced gut tumorigenesisSemantic proximity Read ↗

Cystathionineβ-Synthase in Physiology and CancerSemantic proximity Read ↗

Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes CarcinogenesisSemantic proximity Read ↗

Regulation of Cysteinyl Leukotriene Receptor 2 Expression—A Potential Anti-Tumor MechanismSemantic proximity Read ↗

Loss of CSE couples with BRAF V600E to fuel thyroid cancer metastatic progression through zinc-dependent activation of the EMT machinery.Semantic proximity Read ↗

l-Cys/CSE/H2S pathway modulates mouse uterus motility and sildenafil effect.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.