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Article

The acquisition of malignant potential in colon cancer is regulated by the stabilization of Atonal homolog 1 protein.

Biochemical and biophysical research communications - 1 Mar 2013

Kano Yoshihito, Tsuchiya Kiichiro, Zheng Xiu, Horita Nobukatsu, Fukushima Keita, Hibiya Shuji, Yamauchi Yuhki, Nishimura Tatsunori, Hinohara Kunihiko, Gotoh Noriko, Suzuki Shinji, Okamoto Ryuichi, Nakamura Tetsuya, Watanabe Mamoru

Abstract excerpt

The transcription factor Atonal homolog 1 (Atoh1) plays crucial roles in the differentiation of intestinal epithelium cells. Although we have reported that the Atoh1 protein was degraded in colon cancer by aberrant Wnt signaling, a recent study has indicated that the Atoh1 protein is expressed in...

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PMID: 23333391
DOI: 10.1016/j.bbrc.2013.01.034

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23333391-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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