Article

Interrogation of the glycolytic axis in pulmonary arterial hypertension models and how modifying these can lead to potential therapeutic options

2026-01-14

Abstract excerpt

<h4>Introduction</h4> Pulmonary arterial hypertension (PAH) describes diseases characterized by increased pulmonary vessel pressures that lead to right ventricular failure and death if left untreated. Dysregulated metabolic function has been reported in endothelial cells from PAH patients. Healthy endothelial cells can rapidly shift from quiescence to proliferative and apoptotic states, partly due to a greater ut...

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Literature Corpus work: a9574d39-0133-50a3-9d25-ada49cbae7a2
DOI: 10.64898/2026.01.14.699109

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