Article

Generation of human hindlimb/genital tubercle progenitors from pluripotent stem cells

2026-04-16

Abstract excerpt

The hindlimbs and genital tubercle arise from a bipotent progenitor population within the posterior lateral plate mesoderm (pLPM) and share common genetic programmes, reflecting their deep evolutionary homology. Perturbations of this shared developmental programme underlie several congenital conditions. Yet most insights into the divergence of pLPM fates come from traditional model organisms, emphasising the need...

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Identifiers and source

Literature Corpus work: a9565633-2299-5953-9695-a9491e1abb6c
DOI: 10.64898/2026.04.14.718471

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