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Article

Childhood adiposity and risk of type 1 diabetes: A Mendelian randomization study.

PLoS medicine - 1 Aug 2017

Censin J C, Nowak Christoph, Cooper Nicholas, Bergsten Peter, Todd John A, Fall Tove

Abstract excerpt

BACKGROUND: The incidence of type 1 diabetes (T1D) is increasing globally. One hypothesis is that increasing childhood obesity rates may explain part of this increase, but, as T1D is rare, intervention studies are challenging to perform. The aim of this study was to assess this hypothesis with a Mendelian randomization approach that uses genetic variants as instrumental variables to test for causal associations....

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 28763444
DOI: 10.1371/journal.pmed.1002362
PMCID: PMC5538636

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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