Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Childhood adiposity and novel subtypes of adult-onset diabetes: a Mendelian randomisation and genome-wide genetic correlation study

27 Feb 2023

Abstract excerpt

AIMS/HYPOTHESIS: We investigated whether the impacts of childhood adiposity on adult-onset diabetes differ across proposed diabetes subtypes using a Mendelian randomisation (MR) design. METHODS: We performed MR analysis using data from European genome-wide association studies of childhood adiposity, latent autoimmune diabetes in adults (LADA, proxy for severe autoimmune diabetes), severe insulin-deficient...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipokines, Inflammation, and Metabolic Diseases
Share to Diabetes and associated disorders
Share to Genetic Associations and Epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36843089
DOI: 10.1007/s00125-023-05883-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Childhood adiposity and novel subtypes of adult-onset diabetes: a Mendelian randomisation and genome-wide genetic correlation studyPMID 36843089Read ↗

Heterogeneity in paediatric diabetes clinical presentation and its link to disease severitySemantic proximity Read ↗

Birthweight, BMI in adulthood and latent autoimmune diabetes in adults: a Mendelian randomisation study.Semantic proximity Read ↗

Disentangling the direct and indirect effects of childhood adiposity on type 1 diabetes and immune-associated diseases: a multivariable Mendelian randomization studySemantic proximity Read ↗

Growth and development of islet autoimmunity and type 1 diabetes in children genetically at risk.Semantic proximity Read ↗

Genome-wide analysis reveals extensive genetic overlap between childhood phenotypes and later-life type 2 diabetes.Semantic proximity Read ↗

Childhood adiposity and risk of type 1 diabetes: A Mendelian randomization study.Semantic proximity Read ↗

Aetiological differences between novel subtypes of diabetes derived from genetic associationsSemantic proximity Read ↗

Spectrum of Phenotypes and Causes of Type 2 Diabetes in Children.Semantic proximity Read ↗

Genome-wide association analyses highlight etiological differences underlying newly defined subtypes of diabetes.Semantic proximity Read ↗

Adult-Onset Autoimmune Diabetes in Europe Is Prevalent With a Broad Clinical PhenotypeSemantic proximity Read ↗

Genetic evidence that high BMI in childhood has a protective effect on intermediate diabetes traits, including measures of insulin sensitivity and secretion, after accounting for BMI in adulthood.Semantic proximity Read ↗

Differences in Biomarkers of Inflammation Between Novel Subgroups of Recent-Onset DiabetesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.