Article
The role of alternative splicing in cancer.
Transcription - 15 Mar 2017
Singh Babita, Eyras Eduardo
Abstract excerpt
The functional capacity of cells is defined by the transcriptome. Many recent studies have identified variations in the transcriptome of tumors due to alternative splicing changes, as well as mutations in splicing factors and regulatory signals in most tumor types. Some of these alterations have been linked to tumor progression, metastasis, therapy resistance, and other oncogenic processes. Here, we describe the...
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