Article

Activity of Estrogen Receptor β Agonists in Therapy-Resistant Estrogen Receptor-Positive Breast Cancer

2022-01-17

Abstract excerpt

<h4>Background</h4> Among women, breast cancer is the leading cause of cancer-related death worldwide. Estrogen receptor α positive (ERα+) breast cancer accounts for 70% of all breast cancer subtypes. Although ERα+ breast cancer initially responds to estrogen deprivation or blockade, resistance emergence compelling the use of more aggressive therapies. While ERα is a driver in ERα+ breast cancer, ERβ plays an inh...

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Literature Corpus work: a8cd4f7d-f553-5cec-b090-b39050773f4c
DOI: 10.1101/2022.01.14.476328

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