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Insights into the Role of Estrogen Receptor β in Triple-Negative Breast Cancer

5 Jun 2020

Abstract excerpt

Estrogen receptors (ERα and ERβ) are ligand-activated transcription factors that play different roles in gene regulation and show both overlapping and specific tissue distribution patterns. ERβ, contrary to the oncogenic ERα, has been shown to act as an oncosuppressor in several instances. However, while the tumor-promoting actions of ERα are well-known, the exact role of ERβ in carcinogenesis and tumor...

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PMID: 32516978
DOI: 10.3390/cancers12061477

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