Article

Structural and Functional Diversity among Agonist-Bound States of the GLP-1 Receptor

2021-02-25

Abstract excerpt

<h4>ABSTRACT</h4> Recent advances in G protein-coupled receptor (GPCR) structural elucidation have strengthened previous hypotheses that multi-dimensional signal propagation mediated by these receptors is, in part, dependent on their conformational mobility. However, the relationship between receptor function and static structures determined via crystallography or cryo-electron microscopy is not always clear. Thi...

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Literature Corpus work: a8c66353-3a77-579f-ad70-f0f4c089489a
DOI: 10.1101/2021.02.24.432589

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