Article

Characterization of caffeine response regulatory variants in vascular endothelial cells

2022-11-24

Abstract excerpt

Genetic variants in gene regulatory sequences can modify gene expression and mediate the molecular response to environmental stimuli. In addition, genotype-environment interactions (GxE) contribute to complex traits such as cardiovascular disease. Caffeine is the most widely consumed stimulant and is known to produce a vascular response. To investigate GxE for caffeine, we treated vascular endothelial cells with c...

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Literature Corpus work: a8a872be-61f4-5e5c-bdc8-80fe09e8cb89
DOI: 10.1101/2022.11.22.517533

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