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MPRAVarDB: an online database and web server for exploring regulatory effects of genetic variants.

Bioinformatics (Oxford, England) - 1 Oct 2024

Jin Weijia, Xia Yi, Nizomov Javlon, Liu Yunlong, Li Zhigang, Lu Qing, Chen Li

Abstract excerpt

SUMMARY: Massively parallel reporter assay (MPRA) is an important technology for evaluating the impact of genetic variants on gene regulation. Here, we present MPRAVarDB, an online database and web server for exploring regulatory effects of genetic variants. MPRAVarDB harbors 18 MPRA experiments designed to assess the regulatory effects of genetic variants associated with GWAS loci, eQTLs, and genomic features,...

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PMID: 39325859
DOI: 10.1093/bioinformatics/btae578
PMCID: PMC11464417

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