Article

MYC directly transactivates CR2/CD21, the receptor of the Epstein-Barr virus, enhancing the viral infection of Burkitt lymphoma cells

2023-02-07

Abstract excerpt

<title>Abstract</title> <p>MYC is an oncogenic transcription factor dysregulated in about half of total human tumors. Transcriptomic studies reveal more than 1000 genes regulated by MYC but a much smaller fraction of genes is directly transactivated by MYC. Virtually all Burkitt lymphoma (BL) carry chromosomal translocations involving MYC oncogene. All endemic BL and a fraction of sporadic BL are associated to Ep...

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Literature Corpus work: a8817fcf-77bb-5a18-b17f-7aa94b52734d
DOI: 10.21203/rs.3.rs-2538215/v1

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