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The in vivo binding site for oncoprotein c-Myc in the promoter for Epstein-Barr virus (EBV) encoding RNA (EBER) 1 suggests a specific role for EBV in lymphomagenesis.

Medical science monitor : international medical journal of experimental and clinical research - 1 Jan 2003

Niller Hans H, Salamon Daniel, Ilg Karin, Koroknai Anita, Banati Ferenc, Bauml Gerald, Rucker Ovidiu, Schwarzmann Fritz, Wolf Hans, Minarovits Janos

Abstract excerpt

BACKGROUND: Epstein-Barr virus (EBV) was isolated in the 1960s from the African childhood tumor, Burkitt's Lymphoma (BL), characterized by the translocation of the c-myc gene into one of the immunoglobulin loci. Due to the extreme discrepancy between the widespread dissemination of EBV infection and the overall rarity of EBV-related tumors, it remains an open question whether EBV is really a human tumor virus,...

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PMID: 12552250

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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