Article

Systems-Level Proteomics Evaluation of Microglia Response to Tumor-Supportive Anti-inflammatory Cytokines

2021-02-05

Abstract excerpt

<h4>Background</h4> Microglia safeguard the CNS against injuries and pathogens by inducing an inflammatory response. When exposed to anti-inflammatory cytokines, these cells possess the ability to switch from an inflammatory to an immunosuppressive phenotype. Cancer cells exploit this property to evade the immune system, and elicit an anti-inflammatory microenvironment that facilitates tumor attachment and growth...

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Literature Corpus work: a86ec1f1-5d22-515b-8570-be94ec9919c3
DOI: 10.1101/2021.02.04.429830

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