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Article

In Search for Reliable Markers of Glioma-Induced Polarization of Microglia

15 Jun 2018

Abstract excerpt

Immune cells accumulating in the microenvironment of malignant tumors are tumor-educated, and contribute to its growth, progression and evasion of antitumor immune responses. Glioblastoma (GBM), the common and most malignant primary brain tumor in adults, shows considerable accumulation of resident microglia and peripheral macrophages, and their polarization into tumor-supporting cells. There are controversies...

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PMID: 29963047
DOI: 10.3389/fimmu.2018.01329

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