Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Allelic H3K27me3 to allelic DNA methylation switch maintains noncanonical imprinting in extraembryonic cells.

Science advances - 1 Dec 2019

Chen Zhiyuan, Yin Qiangzong, Inoue Azusa, Zhang Chunxia, Zhang Yi

Abstract excerpt

Faithful maintenance of genomic imprinting is essential for mammalian development. While germline DNA methylation-dependent (canonical) imprinting is relatively stable during development, the recently found oocyte-derived H3K27me3-mediated noncanonical imprinting is mostly transient in early embryos, with some genes important for placental development maintaining imprinted expression in the extraembryonic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Methylation
Share to Embryonic Development
Share to Genome

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genomic Imprinting

Share to Genomics

Share to Histones

Share to Oocytes

Share to Zygote

Source

Open in PubMed Open full text

Identifiers

PMID: 32064321
DOI: 10.1126/sciadv.aay7246
PMCID: PMC6989337

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Allelic H3K27me3 to allelic DNA methylation switch maintains noncanonical imprinting in extraembryonic cells.PMID 32064321Read ↗

Maternal H3K27me3 controls DNA methylation-independent imprinting.Semantic proximity Read ↗

Evolutionary epigenomic analyses in mammalian early embryos reveal species-specific innovations and conserved principles of imprintingSemantic proximity Read ↗

H3K9 methyltransferase EHMT2/G9a controls ERVK-driven non-canonical imprinted genesSemantic proximity Read ↗

Endogenous retroviral insertions drive non-canonical imprinting in extra-embryonic tissuesSemantic proximity Read ↗

Stability and Lability of Parental Methylation Imprints in Development and Disease.Semantic proximity Read ↗

H3K9 Methyltransferase EHMT2/G9a Controls ERVK-Driven Noncanonical Imprinted GenesSemantic proximity Read ↗

Germline-derived DNA methylation and early embryo epigenetic reprogramming: The selected survival of imprintsSemantic proximity Read ↗

Allele-specific H3K9me3 and DNA methylation co-marked CpG-rich regions serve as potential imprinting control regions in pre-implantation embryo.Semantic proximity Read ↗

Dynamic stage-specific changes in imprinted differentially methylated regions during early mammalian development and prevalence of non-CpG methylation in oocytesSemantic proximity Read ↗

Genomic imprinting: employing and avoiding epigenetic processes.Semantic proximity Read ↗

Diverse epigenetic mechanisms maintain parental imprints within the embryonic and extraembryonic lineagesSemantic proximity Read ↗

Allelic reprogramming of the histone modification H3K4me3 in early mammalian development.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.