Article
Cell Cycle Arrest of a ‘Zippering’ Epithelial Cell Cluster Shapes the Face and is Disrupted in Craniofacial Disorders
2025-07-30
Abstract excerpt
Facial features identify individuals, but the mechanisms shaping the human face remain elusive. Orofacial clefting (OFC), the most common craniofacial abnormality, results from failed fusion of the facial prominences that is in part caused by persistence of the cephalic epithelium. Here we uncover the identity, behaviors, and molecular blueprints of a novel craniofacial epithelial population, the Zippering Lambda...
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Identifiers and source
- Literature Corpus work
- a85df85d-40af-5e18-b344-3848e542c8e8
- DOI
- 10.1101/2025.07.28.667310
