Article

Alpha-synuclein deposition patterns in Alzheimer’s disease: association with cortical amyloid beta and variable tau load

2025-07-14

Abstract excerpt

<title>Abstract</title> <p>Alpha-synuclein (α-syn) deposits are common in around half of the Alzheimer’s disease (AD) cases. While direct and indirect protein interactions are suggested, the relationships between different protein aggregates remain poorly understood. Here, we aimed to characterize α-syn, amyloid beta (Aβ), and tau load distributions of AD patients. Protein deposits were automatically quantified w...

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Literature Corpus work: a84cc89f-723e-5920-ba6e-e1d5fb64a08f
DOI: 10.21203/rs.3.rs-7022346/v1

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