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Associations between misfolded alpha‐synuclein aggregates and Alzheimer's disease pathology in vivo

11 Sept 2024

Abstract excerpt

INTRODUCTION: We examined the relations of misfolded alpha synuclein (α-synuclein) with Alzheimer's disease (AD) biomarkers in two large independent cohorts. METHODS: We included Biomarkers for Identifying Neurodegenerative Disorders Early and Reliably Two (BioFINDER-2) and Alzheimer's Disease Neuroimaging Initiative (ADNI) participants (n = 2315, cognitively unimpaired, mild cognitive impairment, AD dementia)...

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PMID: 39258841
DOI: 10.1002/alz.14225

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