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α-synuclein as an emerging pathophysiological biomarker of Alzheimer’s disease

3 Apr 2022

Abstract excerpt

INTRODUCTION: α-syn aggregates represent the pathological hallmark of synucleinopathies as well as a frequent copathology (almost 1/3 of cases) in AD. Recent research indicates a potential role of α-syn species, measured in CSF with conventional analytical techniques, in the differential diagnosis between AD and synucleinopathies (such as DLB). Pioneering studies report the detection of α-syn in blood, however,...

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PMID: 35443850
DOI: 10.1080/14737159.2022.2068952

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