Article

CBR4 is essential for mice but not for skeletal muscle function

2026-07-18

Abstract excerpt

The mitochondrial fatty acid synthesis (mtFAS) pathway is a highly conserved process in mitochondria implicated in metabolic state sensing. Aberrant functioning of this pathway leads to neurodegenerative diseases in humans. Animal experiments indicates that the mtFAS pathway is essential in mammals, and mtFAS inactivation leads to neuronal cell death. Nuclear encoded mitochondrial 3-ketoacyl-acyl carrier protein r...

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Literature Corpus work: a83e91e1-1344-516e-bf80-92d136cad28a
DOI: 10.64898/2026.07.13.738135

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