Article
The respiratory chain supercomplex organization is independent of COX7a2l isoforms.
Cell metabolism - 2 Dec 2014
Mourier Arnaud, Matic Stanka, Ruzzenente Benedetta, Larsson Nils-Göran, Milenkovic Dusanka
Abstract excerpt
The organization of individual respiratory chain complexes into supercomplexes or respirasomes has attracted great interest because of the implications for cellular energy conversion. Recently, it was reported that commonly used mouse strains harbor a short COX7a2l (SCAFI) gene isoform that supposedly precludes the formation of complex IV-containing supercomplexes. This claim potentially has serious implications...
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