Article

Cannabidiol ameliorates mitochondrial disease via PPARγ activation

2023-09-19

Abstract excerpt

<title>Abstract</title> <p>Mutations in mitochondrial energy-producing genes lead to a heterogeneous group of untreatable disorders known as primary mitochondrial diseases (MD). Leigh syndrome (LS) is the most common pediatric MD and is characterized by progressive neuromuscular affectation and premature death. Here, we show that daily cannabidiol (CBD) administration significantly extends lifespan and ameliorate...

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Literature Corpus work: 780877c3-07f1-5745-b520-3ede0521c42d
DOI: 10.21203/rs.3.rs-3231021/v1

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