Article

Cancer-associated Fibroblasts in Pan-Cancer Drive CXCR2+VNN2+ Neutrophils Reprogramming to Mediate Immunosuppression and Immunotherapy Resistance

2025-06-10

Abstract excerpt

<title>Abstract</title> <p>Neutrophils are the most abundant granulocyte population and have important functions such as defense against pathogens. However, they show significant heterogeneity and play more complex roles in tumors. The theory of two-tiered differentiation of neutrophils is insufficient to summarize their phenotypic and functional heterogeneity. Therefore, specific regulatory mechanisms remain to...

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Literature Corpus work: a83c3e41-13d2-5f38-b67c-dbecd707e1ff
DOI: 10.21203/rs.3.rs-6566788/v1

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