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Neutrophils recruited by NKX2-1 suppression via activation of CXCLs/CXCR2 axis promote lung adenocarcinoma progression

2023-11-26

Abstract excerpt

<h4>Background: </h4> Lung adenocarcinoma (LUAD) progression is dependent on the immune tumor microenvironment through paracrine signaling. NKX2-1 is the lineage-specific transcription factor that serves as a well-characterized pathology marker to define LUAD with progressive impact in patients. However, the involvement of NKX2-1 in modeling the tumor immune microenvironment is still unclear. Here, we demonstrated...

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Literature Corpus work
631f72a3-e479-5600-a24e-9bdf09c54d08
DOI
10.21203/rs.3.rs-3646385/v1
Open publication

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Neutrophils recruited by NKX2-1 suppression via activation of CXCLs/CXCR2 axis promote lung adenocarcinoma progressionDOI 10.21203/rs.3.rs-3646385/v1
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