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Tumor‑associated neutrophils: Critical regulators in cancer progression and therapeutic resistance (Review)

25 Feb 2025

Abstract excerpt

Cancer is the second leading cause of death among humans worldwide. Despite remarkable improvements in cancer therapies, drug resistance remains a significant challenge. The tumor microenvironment (TME) is intimately associated with therapeutic resistance. Tumor‑associated neutrophils (TANs) are a crucial component of the TME, which, along with other immune cells, play a role in tumorigenesis, development and...

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PMID: 40017131
DOI: 10.3892/ijo.2025.5734

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