Article

Aryl hydrocarbon receptor activation drives polymorphonuclear myeloid-derived suppressor cell response and efficiently attenuates experimental Sjögren Syndrome

2022-07-05

Abstract excerpt

<title>Abstract</title> <p>Myeloid-derived suppressor cells (MDSCs) are heterogeneous myeloid cell populations with immunosuppressive capacity, which contribute to immune regulation and tolerance induction. We previously reported impaired MDSC function in patients with primary Sjögren’s syndrome (pSS) and mice with experimental SS (ESS). However, the molecular mechanisms underlying MDSCs dysfunction remain large...

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Literature Corpus work: a821ab7b-7591-5b6f-bd00-d4adddf99141
DOI: 10.21203/rs.3.rs-1790811/v1

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