Article

Mitotic bookmarking by CTCF controls selected genes during the fast post-mitotic genome reactivation of ES cells

2022-02-20

Abstract excerpt

Mitosis leads to a global downregulation of transcription that then needs to be efficiently restored. In somatic cells, this is mediated by a transient hyper-active state that first leads to the reactivation of genes necessary to rebuild the interphasic cell and then of those executing specific cell functions. Here, we hypothesized that cells displaying rapid cell cycles may display accelerated gene reactivation d...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a80bc581-9be8-51d8-ae7c-d0b468bb2ac7
DOI: 10.1101/2022.02.20.481195

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Mitotic bookmarking by CTCF controls selected genes during the fast post-mitotic genome reactivation of ES cellsDOI 10.1101/2022.02.20.481195Read

Mitotic Gene Bookmarking: An Epigenetic Program to Maintain Normal and Cancer Phenotypes.Semantic proximity Read

Regulation of transcription reactivation dynamics exiting mitosisSemantic proximity Read

Mitotic bookmarking of genes: a novel dimension to epigenetic control.Semantic proximity Read

Architectural epigenetics: mitotic retention of mammalian transcriptional regulatory information.Semantic proximity Read

Bookmarking target genes in mitosis: a shared epigenetic trait of phenotypic transcription factors and oncogenes?Semantic proximity Read

Chromatin remodelling enables enhancer resetting to facilitate the ERK transcriptional responseSemantic proximity Read

Single-cell landscape of nuclear configuration and gene expression during stem cell differentiation and X inactivation.Semantic proximity Read

A temporally controlled sequence of X-chromosome inactivation and reactivation defines female mouse <i>in vitro</i> germ cells with meiotic potentialSemantic proximity Read

Transcription factor networks in cellular quiescenceSemantic proximity Read

Study of mitotic chromatin supports a model of bookmarking by histone modifications and reveals nucleosome deposition patternsSemantic proximity Read

An H4K20me3-CTCF switch at stable TAD boundaries enforces reversible cell state transitionsSemantic proximity Read

Single cell multiomics approach to analyze replication timing and gene expression in mouse preimplantation embryosSemantic proximity Read