Article

Transcriptomics Analyses of ALS Post-mortem Motor Cortex highlight alteration and potential biomarkers in the Neuropeptide Signalling pathway

2023-05-05

Abstract excerpt

<h4>Background</h4> Amyotrophic lateral sclerosis (ALS) is a fatal heterogeneous neurodegenerative disease that typically leads to death from respiratory failure within two to five years. Despite the identification of several genetic risk factors, the biological processes involved in ALS pathogenesis remain poorly understood. The motor cortex is an ideal region to study dysregulated pathological processes in ALS a...

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Literature Corpus work: a7e80388-db79-5ff0-b1ce-77a17c0418df
DOI: 10.1101/2023.05.05.23289551

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