Article

Characterization of the minimal residual disease state reveals distinct evolutionary trajectories of human glioblastoma

2022-01-29

Abstract excerpt

Recurrence of solid tumors renders patients vulnerable to a distinctly advanced, highly treatment-refractory disease state that has an increased mutational burden and novel oncogenic drivers not detected at initial diagnosis. Improving outcomes for recurrent cancers requires a better understanding of cancer cell populations that expand from the post-therapy, minimal residual disease (MRD) state. We profiled barcod...

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Literature Corpus work: a7bde6f7-e581-533e-9189-c64b3b25d5d2
DOI: 10.1101/2022.01.28.478232

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