Article

Preferential boosting of SARS-CoV-2 Omicron lineage-specific immune responses by monovalent XBB.1.5 vaccination

2025-11-02

Abstract excerpt

Ongoing escape from pre-existing antibodies by severe acute respiratory distress syndrome coronavirus-2 (SARS-CoV-2) necessitates yearly coronavirus disease 2019 (COVID-19) vaccine updates for at-risk populations. Monovalent variant-specific booster vaccines, such as those for XBB.1.5, JN.1, and LP.8.1, aim to re-direct immune responses towards antigenically distinct variants; However, immune imprinting by multipl...

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Literature Corpus work: a7a2d89e-883a-5bd8-91a0-5625814c886e
DOI: 10.1101/2025.10.30.25339006

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