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Article

Fucoidans are senotherapeutics that enhance SIRT6-dependent DNA repair

2025-04-28

Abstract excerpt

<h4>ABSTRACT</h4> Aging is marked by the accumulation of senescent cells (SnCs), which contribute to tissue dysfunction and age-related diseases. Senotherapeutics, including senolytics which specifically induce lysis of SnCs and senomorphics, which suppress the senescence phenotype, represent promising therapeutic interventions for mitigating age-related pathologies and extending healthspan. Using a phenotypic-ba...

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Literature Corpus work
a79e8a39-7c7f-5ff8-bb91-078a118063ea
DOI
10.1101/2025.04.27.650852
Open publication

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Fucoidans are senotherapeutics that enhance SIRT6-dependent DNA repairDOI 10.1101/2025.04.27.650852
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