Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Intersection of Epigenetics and Senolytics in Mechanisms of Aging and Therapeutic Approaches

26 Dec 2024

Abstract excerpt

The biological process of aging is influenced by a complex interplay of genetic, environmental, and epigenetic factors. Recent advancements in the fields of epigenetics and senolytics offer promising avenues for understanding and addressing age-related diseases. Epigenetics refers to heritable changes in gene expression without altering the DNA sequence, with mechanisms like DNA methylation, histone modification,...

Topics

Join the communities discussing this publication.

Epigenetics and DNA Methylation
Genetics, Aging, and Longevity in Model Organisms
Telomeres, Telomerase, and Senescence

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 39858413
DOI: 10.3390/biom15010018

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Intersection of Epigenetics and Senolytics in Mechanisms of Aging and Therapeutic ApproachesPMID 39858413Read ↗

Discovery, development, and future application of senolytics: theories and predictions.Semantic proximity Read ↗

The senescent cell epigenomeSemantic proximity Read ↗

Senolytics: Targeting Senescent Cells for Age-Associated DiseasesSemantic proximity Read ↗

Senolytics and Senostatics: A Two-Pronged Approach to Target Cellular Senescence for Delaying Aging and Age-Related Diseases.Semantic proximity Read ↗

Targeting Senescence: A Review of Senolytics and Senomorphics in Anti-Aging InterventionsSemantic proximity Read ↗

Senolytic Drugs: Reducing Senescent Cell Viability to Extend Health Span.Semantic proximity Read ↗

Oxidative Stress Induced Senescence Gives Rise to Transcriptionally Distinct Physiological StatesSemantic proximity Read ↗

Targeting Cellular Senescence for Age-Related Diseases: Path to Clinical TranslationSemantic proximity Read ↗

Cellular senescence: a key therapeutic target in aging and diseasesSemantic proximity Read ↗

A second generation of senotherapies: the development of targeted senolytics, senoblockers and senoreversers for healthy ageingSemantic proximity Read ↗

Senolytics: A Translational Bridge Between Cellular Senescence and Organismal AgingSemantic proximity Read ↗

Current senolytics: Mode of action, efficacy and limitations, and their future.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.