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Fucoidans are senotherapeutics that enhance SIRT6-dependent DNA repair

2025-06-06

Abstract excerpt

<title>Abstract</title> <p>Aging is marked by the accumulation of senescent cells (SnCs), which contribute to tissue dysfunction and age-related diseases. Senotherapeutics, including senolytics which specifically induce lysis of SnCs and senomorphics, which suppress the senescence phenotype, represent promising therapeutic interventions for mitigating age-related pathologies and extending healthspan. Using a phen...

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Literature Corpus work
297ac6c0-61fb-5fe7-80f0-8e0f324848a7
DOI
10.21203/rs.3.rs-6613032/v1
Open publication

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