Article

Transcriptomic signatures and network-based methods uncover new Senescent Cell Anti-Apoptotic Pathways and Senolytics

2024-05-30

Abstract excerpt

Cellular senescence is an irreversible cell cycle arrest caused by various stressors that damage cells. Over time, senescent cells accumulate and contribute to the progression of multiple age-related degenerative diseases. It is believed that these cells accumulate partly due to their ability to evade programmed cell death through the development and activation of survival and anti-apoptotic resistance mechanisms;...

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Literature Corpus work: f709a5e5-78e3-580e-9549-05630bc45ee0
DOI: 10.1101/2024.05.28.596326

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