Article

Reverse engineering glaucoma

2018-01-01

Abstract excerpt

Primary open angle glaucoma (POAG) is a leading cause of irreversible blindness worldwide, and the only modifiable risk factor is intraocular pressure (IOP). Glaucoma is a complex disease with specific endophenotypes, and disease pathogenesis is likely to involve multiple pathways linking genetic and environmental interactions. Growth factors present in the aqueous humour in POAG increase outflow resistance and el...

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Literature Corpus work: 78179d1d-ae95-5075-a61a-adc59f6d7356
DOI: 10.17638/03022786

Open publication

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