Article

Non-canonical induction of autophagy increases adeno-associated virus type 2 (AAV2) transduction efficiency

2024-01-11

Abstract excerpt

<h4>ABSTRACT</h4> Adeno-associated virus (AAV) serotypes infect a wide range of cell types, making this member of the parvovirus family a versatile tool in gene therapy. Infection as well as transduction is set in motion by means of specific receptors in conjunction with trafficking pathways, particularly endocytosis, a main cell entry pathway of non-enveloped viruses. Here, we report that efficacy of transductio...

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Literature Corpus work: a76e655f-3a8e-5405-b7c5-a3e03c2029c4
DOI: 10.1101/2024.01.08.574727

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Non-canonical induction of autophagy increases adeno-associated virus type 2 (AAV2) transduction efficiencyDOI 10.1101/2024.01.08.574727Read

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