Back to search

Article

Rab9 depletion enhances human adenovirus type 26 transduction efficiency through increased internalization and reduced late endosomal/lysosomal retention

2026-02-26

Abstract excerpt

Understanding intracellular trafficking is critical for viral pathogenesis and for the rational design of viral vectors, as endocytic routing determines genome release, immune sensing, and overall transduction efficiency. Human adenovirus type 26 (HAdV-D26) presents a promising platform for vector design due to its low preexisting immunity, potent immune stimulation, scalable production, and versatile genetic engi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
75227540-8148-5792-ba92-845566f9c8d0
DOI
10.64898/2026.02.24.707667
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Rab9 depletion enhances human adenovirus type 26 transduction efficiency through increased internalization and reduced late endosomal/lysosomal retentionDOI 10.64898/2026.02.24.707667
Adenovirus – a blueprint for gene deliverySemantic proximity
In Vitro and In Vivo Evaluation of Human Adenovirus Type 49 as a Vector for Therapeutic ApplicationsSemantic proximity
Efficient clathrin-mediated entry of enteric adenoviruses in human duodenal cellsSemantic proximity
Efficient clathrin-mediated entry of enteric adenoviruses in human duodenal cellsSemantic proximity
Intracellular trafficking of adenovirus: Many means to many ends☆Semantic proximity
Divergent Entry, Convergent Trafficking in Defensin-Mediated Adenovirus InfectionSemantic proximity
Cargo and biological properties of extracellular vesicles released from human adenovirus type 4-infected lung epithelial cellsSemantic proximity
Expanding the adenovirus toolbox: reporter viruses for studying the dynamics of human adenovirus replicationSemantic proximity
ORF3a of SARS-CoV-2 promotes lysosomal exocytosis-mediated viral egressSemantic proximity
Adenovirus Entry: From Infection to ImmunitySemantic proximity
Imaging the adenovirus infection cycleSemantic proximity
The fiber knob protein of human adenovirus type 49 mediates highly efficient and promiscuous infection of cancer cell lines using a novel cell entry mechanismSemantic proximity
Select a neighboring publication to make it the new centre.