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Article

Enhancing gene delivery of adeno-associated viruses by cell-permeable peptides

1 Jan 2014

Abstract excerpt

Adeno-associated virus type 2 (AAV2) is considered a promising gene delivery vector and has been extensively applied in several disease models; however, inefficient transduction in various cells and tissues has limited its widespread application in many areas of gene therapy. In this study, we have developed a general, but efficient, strategy to enhance viral transduction, both in vitro and in vivo, by incubating...

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PMID: 26015948
DOI: 10.1038/mtm.2013.12

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