Article

Deletion of the ion channel <i>Trpm4</i> increases cardiac inflammatory markers and fibrosis after myocardial infarction in mice

2022-10-24

Abstract excerpt

<h4>ABSTRACT</h4> <h4>BACKGROUND</h4> The first cause of mortality worldwide is ischemic heart disease. In myocardial infarction (MI), the ischemic event causes cell death, which triggers a large inflammatory response responsible for removing necrotic material and inducing tissue repair. Endothelial cells, immune cells and fibroblasts play a key role in orchestrating this healing process. TRPM4 is a Ca 2+ -acti...

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Literature Corpus work: a7155beb-5fe9-5674-a2e7-ccae53b444e5
DOI: 10.1101/2022.10.24.513479

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