Article
Elaboration of a MALDI-TOF Mass Spectrometry-based Assay of Parkin Activity and High-Throughput screening platform for Parkin Activators
2022-03-04
Abstract excerpt
Parkinson’s disease (PD) is a progressive neurological disorder that manifests clinically as alterations in movement (bradykinesia, postural instability, loss of balance, and resting tremors) as well as multiple non-motor symptoms including but not limited to cognitive and autonomic abnormalities. Mitochondrial dysfunction has been linked to sporadic PD and loss-of-function mutations in genes encoding the ubiquiti...
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Identifiers and source
- Literature Corpus work
- a70e0a8c-b719-5db9-84ef-2a98d9347abf
- DOI
- 10.1101/2022.03.04.482851