Article

Identification of deubiquitylases involved in Parkin-mediated mitophagy

2014-01-01

Abstract excerpt

Ubiquitylation is a post-translational modification of proteins with a broad range of downstream effects, ranging from protein turnover to transcriptional regulation, membrane trafficking and DNA damage repair. The conjugation of ubiquitin to its substrate is a sequential process mediated by three enzymes, termed the E1 ubiquitin-activating enzyme, the E2 ubiquitin-conjugating enzyme and the E3 ubiquitin ligase. C...

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Literature Corpus work: 4c745072-31ea-561b-bd24-eaa675c75311
DOI: 10.17638/02003824

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